Real Time Intraoperative Functional Brain Mapping Based on RGB Imaging

Intraoperative optical imaging is a localization technique for the functional areas of human brain cortex during neurosurgical procedures. However, it still lacks robustness to be used as clinical standard. In particular new biomarkers functionality with improved sensitivity and specificity are needed. We present method real time identification activated cortical based on analysis hemodynamic using RGB camera white light source. measure quantitative oxy deoxy-hemoglobin concentration changes in modified Beer-Lambert law Monte Carlo simulations. A model has been implemented define binary biomarker activation following neuronal by physiological stimuli. The results show good correlation between computed maps localized electrical stimulation. demonstrate that combined modeling hemodynamics can evaluate neurosurgery serve tool choice complement